Trilostane Dose For Dogs

Cushing s disease and vetoryl trilostane cushing s disease is a uncommon condition in older dogs often mistaken for the aging process itself.

Trilostane dose for dogs.

Indicated for the treatment of pituitary dependent hyperadrenocorticism in dogs and the treatment of hyperadrenocorticism due to adrenocortical tumor in dogs. While many vets have used trilostane for years the fda has also approved it for the treatment of cushing s in. Vetoryl trilostane approved by the fda in 2008 is the only drug approved to treat both pituitary and adrenal dependent cushing s in dogs. Cushing s disease is a fairly rare endocrine diseases of dogs.

Vetoryl capsules are indicated for the treatment of hyperadrenocorticism due to adrenocortical tumor in dogs. The treatment helps balance the hormone levels to provide relief and control cushing s over the long term. Vetoryl capsules trilostane 120 mg. Always follow the dosage instructions from your veterinarian.

Trilostane is a short acting medication that typically stops working within 24 hours and is generally well tolerated. The starting dose for the treatment of hyperadrenocorticism in dogs is 1 0 3 0 mg lb 2 2 6 7 mg kg once a day. How trilostane works for dogs. These two dogs had clinical signs consistent with hypoadrenocorticism lethargy anorexia collapse and post acth cortisol levels 0 3 µg dl.

Always provide the client information sheet with prescription. However side effects can include lethargy vomiting diarrhea and lack of appetite during the first few days of therapy. Vetoryl trilostane capsules dosage and administration. Trilostane affects the imbalance of the hormone cortisol which is released by the adrenal glands.

Trilostane dosage for dogs. Mean trilostane dosage at 1 year reevaluation in dogs with a good response was 1 7 mg kg 0 8 mg lb twice daily or 1 1 mg kg 3 times daily. Two dogs developed hypoadrenocorticism during the study. This dog responded to trilostane discontinuation and supportive care.

Trilostane vetoryl is indicated for the treatment of pituitary dependant hyperadrenocorticism and treatment of hyperadrenocorticism due to adrenocortical tumors in dogs. Reducing the dose and slowly increasing to the recommended schedule may reduce the side effects. This prescription drug works by stopping the. Trilostane works in dogs by inhibiting cortisol production in the adrenal gland.

Twenty three dogs with pdh had their dose or frequency of trilostane administration increased during the study.